Research Interests


Our research focuses on the structure-function relationships of the key macromolecules that are involved in various biological processes.  Three-dimensional structures of the interested macromolecules have been determined at atomic resolution by a single crystal X-ray diffraction method. Site-directed mutageneses and enzyme kinetics measurements have been used to interpret the structure-function relationships.


Specific research interests:

1.   Enzymes in the methyl cycle

2.   Enzymes involved in prostaglandin biosynthesis

3.   DNA and RNA binding agents

4.   Etc.